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Symbol
Name
ID
Il17f
interleukin 17F
MGI:2676631
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgE level
Cutaneous anergy
Hypereosinophilia
Abnormal B cell count
Abnormal proportion of CD4-positive T cells
Abnormal proportion of CD8-positive T cells
Abnormal natural killer cell count
Recurrent aphthous stomatitis
Blepharitis
Lymphadenopathy
Hepatitis
Recurrent urinary tract infections
Abnormality of the immune system
Seborrheic dermatitis
Chronic mucocutaneous candidiasis
Chronic oral candidiasis
Recurrent vulvovaginal candidiasis
Skin rash
Immunodeficiency
Chronic tinea infection
Candida esophagitis
Phaeohyphomycosis
Recurrent infections
Onychomycosis
Recurrent respiratory infections
Recurrent viral infections
Meningitis
Deep dermatophytosis
Disease(s) Associated with IL17F
chronic mucocutaneous candidiasis

Mouse Phenotypes
immune system phenotype
increased T cell proliferation
decreased susceptibility to induced colitis
absent gamma-delta T cells
increased gamma-delta T cell number
abnormal effector T cell morphology
increased IgG2a level
abnormal immune system physiology
decreased interleukin-17 secretion
decreased susceptibility to experimental autoimmune encephalomyelitis
decreased acute inflammation
chronic inflammation
lung inflammation
increased susceptibility to bacterial infection
Availability Mouse Genotype
Il17a/Il17ftm1.1Impr/Il17a/Il17ftm1.1Impr *
Il17ftm1Awai/Il17ftm1Awai
Il17ftm1Cdon/Il17ftm1Cdon
Il17ftm1Yiw/Il17ftm1Yiw
Il17ftm1Awai/Il17f+
Tg(Scgb1a1-Il17f,GFP)1Cdon/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory